Hyaluronic acid in Bucharest

Author: Revivera medical team · Last updated: 5 October 2026

Hyaluronic acid treatments at Revivera Clinic provide volume support, contouring and tissue hydration using premium fillers, given by doctors experienced in aesthetic medicine. The procedure is carried out after a free medical consultation. On this page you will find information about injectable hyaluronic acid: which areas it is used for, which fillers we use and how they differ, how long the effect lasts, what the studies say and when it is not given.

What is injectable hyaluronic acid

Hyaluronic acid is a substance found naturally in the skin, where it helps keep tissues hydrated and supported. Hyaluronic acid fillers are gels in which the hyaluronic acid is “bound” (cross-linked), which makes it stay longer in the tissue and provide volume and support [1].

Fillers are not all the same: the firmness and cohesion of the gel determine the area it suits. More fluid gels are used for the lips and fine lines, and higher-density gels for the cheekbones, chin and jawline [1]. That is why the doctor chooses the product according to the area and the result you want.

Treatment areas

• Lips — redefining the lip border, tissue hydration and volume support
• Nasolabial folds and deep lines — softening the folds while preserving facial expression
• Cheekbones and midface — restoring volume lost with age [4]
• Chin and jawline — redefining the contour and the profile

The choice of product and injection technique is made individually by the doctor, after an anatomical and functional assessment of the face.

The fillers we use at Revivera

Filler	Recommended for
Restylane Kiss	lip volume and definition
Teosyal Kiss	lip augmentation and hydration
RHA Kiss	natural-looking lips that follow movement
Restylane Defyne	deep lines and nasolabial folds
Teosyal RHA 3	lines, cheekbones and facial contour
Teosyal RHA 4	volumising and redefining the jawline
Restylane Wise	sculpting the contours: cheekbones, jawline
Voluma	restoring volume in the cheekbones and contours

The RHA range is made with a technology that preserves long hyaluronic acid chains, so the gel follows the natural movements of the face [13]. Voluma is a volumising gel for the cheekbone area, studied for correcting midface volume loss [4].

How long the effect lasts

Hyaluronic acid is gradually and naturally reabsorbed by the body through enzyme activity [5]. How long the result lasts depends on the type of gel and its degree of cross-linking, the injected area, and also on your individual metabolism, lifestyle and the blood supply of the area:

• lips: the estimated average duration is around 9–12 months;
• cheekbones and jawline: 12–18 months.

The exact estimate is discussed after your individual medical consultation, and maintaining the result requires periodic maintenance sessions.

How the session works at Revivera

1. Free medical consultation — the doctor assesses the anatomy of your face and your medical history and decides whether the procedure is appropriate.
2. Preparing the area — the skin is cleansed and disinfected; a local anaesthetic can be applied for comfort.
3. Injection — the filler is injected by the doctor, with a needle or a cannula, depending on the area.
4. Aftercare — the doctor gives you aftercare advice for home and, if needed, a follow-up appointment is scheduled.

The session takes around 50 minutes, including the consultation and preparation.

Safety and possible reactions

Most reactions are mild and temporary: swelling, bruising, tenderness or small lumps at the injection site, which usually settle within a few days to a few weeks [3] [6]. On the lips, swelling and bruising are common in the first few days [6].

Serious complications are rare: blockage of a blood vessel (vascular occlusion) is very rare [10], and damage to vision is exceptional [9]. The risk is reduced by knowledge of anatomy and by the doctor’s experience, and recognising and treating a complication quickly is essential [2] [11].

Contraindications

Hyaluronic acid treatment is not given:

• during pregnancy and breastfeeding
• when there is an active infection or inflammation in the area to be treated
• if you have a known allergy to hyaluronic acid or to the product’s ingredients, including the local anaesthetic in products that contain one

Tell the doctor at the consultation if you take anticoagulants or antiplatelet medicines, if you have an autoimmune disease [8] or, for lip treatment, if you have had cold sores. The doctor assesses each case.

Dissolving hyaluronic acid

One advantage of hyaluronic acid fillers is that they can be dissolved, if needed, with an enzyme called hyaluronidase. It is used to correct an unwanted result, an excess of product or lumps, and to treat complications [11] [12]. Read more about dissolving hyaluronic acid.

What the studies say about hyaluronic acid

• Gel properties. The result depends mainly on the viscoelasticity and cohesion of the gel, which is why each product suits certain areas [1].
• Lips. Randomised clinical trials show improved lip volume after treatment, still present in a large share of patients after one year [7]. A meta-analysis of 16 randomised clinical trials found moderate to high satisfaction [6].
• Cheekbones. A clinical study of 235 patients showed that midface volume correction lasted between 15 and 24 months, depending on the area [4].
• Nasolabial folds. A 64-week randomised clinical trial confirmed the effectiveness of a filler from the resilient hyaluronic acid range for nasolabial folds [13].
• Safety. A systematic review of 48 randomised clinical trials shows that most reactions are local and settle within a few weeks, and severe events are rare [3].

Hyaluronic acid, botulinum toxin or biostimulators?

Hyaluronic acid restores volume and contours, with a visible effect straight away. Botulinum toxin relaxes the muscles behind expression lines (forehead, between the eyebrows, around the eyes). Biostimulators, such as Sculptra, gradually stimulate your own collagen production. The treatments can be combined, on the doctor’s recommendation.

Frequently asked questions

How long does hyaluronic acid last?

It depends on the type of gel, the area and your metabolism: around 9–12 months for the lips and 12–18 months for the cheekbones and jawline. The exact estimate is discussed at the consultation, and maintaining the result requires periodic maintenance sessions.

Does hyaluronic acid injection hurt?

A local anaesthetic can be applied, and many fillers contain an anaesthetic, for comfort. The sensation is usually well tolerated.

How long does lip swelling last after hyaluronic acid?

Swelling and any bruising are common in the first few days and usually settle within a week. The final result shows once the swelling has gone down.

Does the result look natural?

The doctor chooses the product and the amount according to the anatomy of your face and the result you want, for a balanced look.

Can hyaluronic acid be dissolved?

Yes. Hyaluronic acid fillers can be dissolved with hyaluronidase if the result is not what you wanted or if a complication occurs.

Is hyaluronic acid treatment safe?

Given by an experienced doctor after a consultation, it has a good safety profile. Reactions are generally mild and temporary, and serious complications are rare.

What should I do after the treatment?

It is usually recommended to avoid intense exercise, saunas and massaging the area for the first few days. The doctor gives you advice for the treated area.

What is the difference between the lip fillers?

Restylane Kiss, Teosyal Kiss and RHA Kiss differ in the texture and firmness of the gel and in how they follow lip movement. The doctor recommends the right one at the consultation.

How much does hyaluronic acid treatment cost?

The price depends on the filler and is charged per ml: between 1,100 and 1,300 lei/ml, depending on the product. Each filler’s price is shown on its page, and the amount needed is decided at the consultation.

Do I need an appointment?

Yes, an appointment is required. Aesthetic treatments have a different schedule from the clinic’s opening hours, so please book in advance.

Scientific sources

1. Pierre S. et al. (2015). Basics of dermal filler rheology. Dermatologic Surgery. https://doi.org/10.1097/DSS.0000000000000334
2. Signorini M. et al. (2016). Global Aesthetics Consensus: Avoidance and Management of Complications from Hyaluronic Acid Fillers. Plastic and Reconstructive Surgery. https://pmc.ncbi.nlm.nih.gov/articles/PMC5242216/
3. Kyriazidis I. et al. (2024). Adverse Events Associated with Hyaluronic Acid Filler Injection for Non-surgical Facial Aesthetics: A Systematic Review of High Level of Evidence Studies. Aesthetic Plastic Surgery. https://doi.org/10.1007/s00266-023-03465-1
4. Glaser D.A. et al. (2015). Duration of Effect by Injection Volume and Facial Subregion for a Volumizing Hyaluronic Acid Filler in Treating Midface Volume Deficit. Dermatologic Surgery. https://doi.org/10.1097/DSS.0000000000000416
5. Faivre J. et al. (2024). Comparison of Hyaluronidase-Mediated Degradation Kinetics of Commercially Available Hyaluronic Acid Fillers In Vitro. Aesthetic Surgery Journal. https://pmc.ncbi.nlm.nih.gov/articles/PMC11093662/
6. Edward Wen Y. et al. (2026). Efficacy and Safety of Hyaluronic Acid Lip Fillers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Aesthetic Surgery Journal. https://doi.org/10.1093/asj/sjaf224
7. Geronemus R.G. et al. (2017). Safety and Effectiveness of VYC-15L, a Hyaluronic Acid Filler for Lip and Perioral Enhancement: One-Year Results From a Randomized Controlled Study. Dermatologic Surgery. https://doi.org/10.1097/DSS.0000000000001035
8. Pieretti G. et al. (2023). Hyaluronic acid fillers in patients with autoimmune diseases: a review. Journal of Cosmetic Dermatology. https://doi.org/10.1111/jocd.15751
9. Chatrath V. et al. (2019). Soft-tissue Filler-associated Blindness: A Systematic Review of Case Reports and Case Series. Plastic and Reconstructive Surgery – Global Open. https://pmc.ncbi.nlm.nih.gov/articles/PMC6554164/
10. Alam M. et al. (2021). Rates of Vascular Occlusion Associated With Using Needles vs Cannulas for Filler Injection. JAMA Dermatology. https://pmc.ncbi.nlm.nih.gov/articles/PMC7774041/
11. Cohen J.L. et al. (2015). Treatment of Hyaluronic Acid Filler-Induced Impending Necrosis With Hyaluronidase: Consensus Recommendations. Aesthetic Surgery Journal. https://doi.org/10.1093/asj/sjv018
12. Kroumpouzos G., Treacy P. (2024). Hyaluronidase for Dermal Filler Complications: Review of Applications and Dosage Recommendations. JMIR Dermatology. https://pmc.ncbi.nlm.nih.gov/articles/PMC10836581/
13. Kaufman-Janette J. et al. (2019). Efficacy and safety of a new resilient hyaluronic acid dermal filler, in the correction of moderate-to-severe nasolabial folds: A 64-week, prospective, multicenter, controlled, randomized, double-blind and within-subject study. Journal of Cosmetic Dermatology. https://pmc.ncbi.nlm.nih.gov/articles/PMC7384057/